Biology Crossword Puzzles
Build biology vocabulary with printable crossword puzzles, review crosswords, answer keys, study sheets, quizzes, and extra practice resources.
Perfect for classroom, homework, tutoring, homeschooling, or weekend practice.
These biology resources help students review key terms from cell biology, genetics, ecology, evolution, and other major life science topics. Use the study sheets to preview vocabulary, assign printable crosswords for practice, and use quizzes or review crosswords for extra reinforcement.
Why use biology crossword puzzles?
Crossword practice gives students repeated exposure to important biology terms in a format that feels more active than simple memorization. It can strengthen spelling, recall, and understanding of scientific vocabulary.
Because the sets are organized by study sheets, teachers and parents can assign smaller groups of terms, repeat them later with different crossword versions, and build long-term retention across the school year.
Best ways to use this page
Start with a study sheet, assign the matching crossword, and then check work with the answer key. For extra review, use the online quizzes for Sets 1–8 and the full Biology 120 Vocabulary Game for broader mixed practice.
Biology study sheets
Use these study sheets to introduce or review the 120 biology terms before assigning printable crossword practice.
Biology vocabulary crossword puzzles
These 32 printable crosswords are organized for direct classroom use. The first 8 sets also include matching online quizzes.
Review 120 biology terms
Each review crossword covers 24 of the 120 terms and works well for spiral review, reteaching, or end-of-unit practice.
| Review Set | Printable Review Crossword | Answer Key |
|---|---|---|
| 1 | Review Crossword 1 | Answer Key 1 |
| 2 | Review Crossword 2 | Answer Key 2 |
| 3 | Review Crossword 3 | Answer Key 3 |
| 4 | Review Crossword 4 | Answer Key 4 |
| 5 | Review Crossword 5 | Answer Key 5 |
| 6 | Review Crossword 6 | Answer Key 6 |
| 7 | Review Crossword 7 | Answer Key 7 |
| 8 | Review Crossword 8 | Answer Key 8 |
| 9 | Review Crossword 9 | Answer Key 9 |
| 10 | Review Crossword 10 | Answer Key 10 |
| 11 | Review Crossword 11 | Answer Key 11 |
| 12 | Review Crossword 12 | Answer Key 12 |
More biology crossword puzzles
These additional biology crossword PDFs provide extra practice for students who need more review.