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AP Biology Crossword Puzzles

AP Biology Crossword Puzzles
High School Science Vocabulary

AP Biology Crossword Puzzles

Perfect for classroom, homework, tutoring, homeschooling, or weekend practice.

Build stronger AP Biology vocabulary with printable crossword puzzles, review crosswords, study sheets, quizzes, and interactive practice. This page is designed to help students review key terms from molecular biology, genetics, evolution, ecology, and other major AP Biology topics in a more engaging way.

Teachers can use these resources for warm-ups, stations, homework, extra review, sub plans, or test preparation. Students can print puzzles, complete them independently, and check their understanding with answer pages and additional review tools.

AP Biology 120 Vocabulary Game AP Biology Quizzes and Tests

Why use AP Biology crossword puzzles?

Review key vocabulary

Crossword practice helps students repeatedly see and apply important academic science terms in a focused format.

Support exam preparation

These puzzles give students extra review with the terminology they need to understand major AP Biology concepts and exam questions.

Make practice more active

Instead of passive rereading, students solve clues, recall definitions, and strengthen retention through active practice.

Teacher tip: Several crossword numbers use the same study-sheet term set but in a different puzzle layout, which makes it easy to assign repeated review without giving students the exact same grid each time.

Study sheets by term set

Use the study sheets before assigning a puzzle, or as a follow-up review tool after students complete one.

Study Sheet 115 terms • used by Crosswords 1, 8, 15, and 22 Study Sheet 215 terms • used by Crosswords 2, 9, 16, and 23 Study Sheet 315 terms • used by Crosswords 3, 10, 17, and 24 Study Sheet 415 terms • used by Crosswords 4, 11, 18, and 25 Study Sheet 515 terms • used by Crosswords 5, 12, 19, and 26 Study Sheet 615 terms • used by Crosswords 6, 13, 20, and 27 Study Sheet 716 terms • used by Crosswords 7, 14, 21, and 28 All TermsComplete AP Biology study sheet for full review

Printable AP Biology crossword puzzles

Choose any puzzle below. Each puzzle includes a matching answer page.

Crossword 1

Open Puzzle PDFOpen Answer Page

Crossword 2

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Crossword 3

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Crossword 4

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Crossword 5

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Crossword 6

Open Puzzle PDFOpen Answer Page

Crossword 7

Open Puzzle PDFOpen Answer Page

Crossword 8

Open Puzzle PDFOpen Answer Page

Crossword 9

Open Puzzle PDFOpen Answer Page

Crossword 10

Open Puzzle PDFOpen Answer Page

Crossword 11

Open Puzzle PDFOpen Answer Page

Crossword 12

Open Puzzle PDFOpen Answer Page

Crossword 13

Open Puzzle PDFOpen Answer Page

Crossword 14

Open Puzzle PDFOpen Answer Page

Crossword 15

Open Puzzle PDFOpen Answer Page

Crossword 16

Open Puzzle PDFOpen Answer Page

Crossword 17

Open Puzzle PDFOpen Answer Page

Crossword 18

Open Puzzle PDFOpen Answer Page

Crossword 19

Open Puzzle PDFOpen Answer Page

Crossword 20

Open Puzzle PDFOpen Answer Page

Crossword 21

Open Puzzle PDFOpen Answer Page

Crossword 22

Open Puzzle PDFOpen Answer Page

Crossword 23

Open Puzzle PDFOpen Answer Page

Crossword 24

Open Puzzle PDFOpen Answer Page

Crossword 25

Open Puzzle PDFOpen Answer Page

Crossword 26

Open Puzzle PDFOpen Answer Page

Crossword 27

Open Puzzle PDFOpen Answer Page

Crossword 28

Open Puzzle PDFOpen Answer Page

AP Biology review crosswords

These review crosswords cover broader mixed-term review and work well for spiral practice, test prep, or whole-class review.

Review Crossword 1

Open Review PuzzleOpen Answer Page

Review Crossword 2

Open Review PuzzleOpen Answer Page

Review Crossword 3

Open Review PuzzleOpen Answer Page

Review Crossword 4

Open Review PuzzleOpen Answer Page

Review Crossword 5

Open Review PuzzleOpen Answer Page

Review Crossword 6

Open Review PuzzleOpen Answer Page

Review Crossword 7

Open Review PuzzleOpen Answer Page

Review Crossword 8

Open Review PuzzleOpen Answer Page

Review Crossword 9

Open Review PuzzleOpen Answer Page

Review Crossword 10

Open Review PuzzleOpen Answer Page

Review Crossword 11

Open Review PuzzleOpen Answer Page

Review Crossword 12

Open Review PuzzleOpen Answer Page

Best ways to use this page

  • Assign one study sheet and one matching crossword for focused vocabulary practice.
  • Use the review crosswords after students have completed several smaller term sets.
  • Pair printable puzzles with the interactive vocabulary game for extra reinforcement.
  • Use quizzes and tests after puzzle practice to check long-term retention.

More AP Biology and science resources

AP Biology 120 Vocabulary GameInteractive matching practice for key AP Biology terms AP Biology Terms Quizzes and TestsCheck understanding with additional AP Biology review Physics 120 Vocabulary GameMore high school science vocabulary practice Physics Terms Crossword PuzzlesPrintable and online physics crossword practice Human Heart Crossword PuzzlePractice anatomy vocabulary with a focused biology puzzle Chemistry Terms CrosswordsExplore additional science crossword practice

SAT Vocabulary Learning System

Use all parts of the SAT vocabulary program to learn, practice, and master the 400 essential SAT words.

SAT Vocabulary Program Overview of the full 400-word study system. SAT Vocabulary Flashcards Study all 400 SAT vocabulary words organized into 20 sets. SAT Vocabulary Crossword Puzzles Practice vocabulary with interactive puzzles. SAT Vocabulary Quizzes Test your understanding of SAT vocabulary. SAT Vocabulary Trainer Interactive vocabulary training activity.
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